Gyne-Lotrimin

Gyne-Lotrimin is a trusted, clinically-proven antifungal medication specifically formulated to treat vaginal yeast infections caused by Candida albicans. Its active ingredient, clotrimazole, targets the fungal cell membrane, leading to rapid symptom relief and eradication of the infection. This over-the-counter solution offers a convenient, discreet, and highly effective option for women seeking prompt management of vulvovaginal candidiasis, backed by decades of medical use and safety data.

Features

• Contains 2% clotrimazole as the active antifungal agent
• Available in cream and insertable tablet formulations
• Designed for intravaginal application with included applicators
• Fragrance-free, dye-free, and hypoallergenic formulation
• Pre-measured doses for accurate and consistent application
• Seven-day and three-day treatment regimens available

Benefits

• Rapid relief from itching, burning, and irritation associated with vaginal yeast infections
• High cure rates demonstrated in clinical studies, with complete eradication of fungal organisms
• Convenient OTC availability without need for prescription, enabling prompt initiation of therapy
• Minimal systemic absorption, ensuring localized action with reduced risk of systemic side effects
• Prevents recurrence by fully eliminating fungal colonization in the vaginal mucosa
• Supports restoration of normal vaginal flora and pH balance post-treatment

Common use

Gyne-Lotrimin is indicated for the treatment of uncomplicated vulvovaginal candidiasis. Symptoms typically include vaginal itching, burning, soreness, and a thick, white, odorless discharge resembling cottage cheese. It is most effective in immunocompetent, non-pregnant women with sporadic infections. Patients with recurrent infections (four or more per year), suspected complicated candidiasis, or who are immunocompromised should seek medical evaluation, as underlying factors may require broader antifungal strategies or oral therapy.

Dosage and direction

Apply once daily, preferably at bedtime, for the prescribed duration (typically 3 or 7 days). Wash hands before and after application. For cream: Fill applicator to the indicated level, insert gently into vagina, and depress plunger. For tablet: Place tablet into applicator, insert into vagina, and push plunger. Remain lying down after application to minimize leakage. External vulvar symptoms may be treated with a thin layer of cream applied twice daily. Complete the full course of treatment even if symptoms resolve earlier to prevent recurrence.

Precautions

Do not use if allergic to clotrimazole or any product ingredients. Avoid contact with eyes. Not for ophthalmic, oral, or cutaneous use beyond labeled indications. Sexual intercourse should be avoided during treatment, as clotrimazole may damage latex condoms and diaphragms. Discontinue use if irritation or sensitivity occurs. Consult a healthcare provider if symptoms persist after treatment, or if fever, pelvic pain, or foul-smelling discharge develops, as these may indicate a different diagnosis.

Contraindications

Hypersensitivity to clotrimazole or other imidazole antifungals. Not for use in patients with known liver dysfunction without medical supervision, although systemic absorption is minimal. Should not be used in cases of suspected bacterial vaginosis, trichomoniasis, or other non-fungal infections. Not recommended during first trimester pregnancy unless directed by a physician.

Possible side effects

Mild and transient burning, itching, or irritation upon application. Skin rash, redness, or swelling may occur infrequently. Very rare systemic reactions include headache, abdominal cramping, or urinary frequency. If severe local reactions or signs of hypersensitivity (hives, difficulty breathing) develop, discontinue use and seek medical attention.

Drug interaction

No significant drug interactions have been reported due to minimal systemic absorption. However, concurrent use with other vaginal products (e.g., douches, spermicides) may alter efficacy or cause irritation. Avoid using with other intravaginal antifungals or corticosteroids unless directed by a clinician.

Missed dose

Apply as soon as remembered, unless close to the next scheduled dose. Do not double the dose. Maintain the regular dosing schedule to ensure consistent therapeutic levels.

Overdose

Overdose is unlikely due to topical application and low systemic absorption. Accidental ingestion may cause gastrointestinal distress; symptomatic treatment is recommended. Excessive vaginal application may increase local irritation—gently cleanse the area if discomfort occurs.

Storage

Store at room temperature (15–30°C). Keep tube or packaging tightly closed. Do not freeze. Keep out of reach of children and pets. Discard unused medication after treatment completion.

Disclaimer

This product is not intended to diagnose, treat, cure, or prevent any disease. Read and follow all label instructions. Consult a healthcare professional for proper diagnosis if this is your first yeast infection, if you are under 12 years of age, pregnant, breastfeeding, or have recurring symptoms. Use only as directed.

Reviews

“Used Gyne-Lotrimin for a recurrent yeast infection—symptoms improved within two days. Completed the 7-day course and had no recurrence. Highly effective.”
“As a nurse, I recommend this OTC option to patients. It’s reliable, easy to use, and backed by clinical evidence.”
“Initially experienced slight burning, but it subsided quickly. Full relief by day 4. Will keep on hand for future use.”