Alli: Clinically Proven Weight Loss Aid for Sustainable Results
Alli
| Product dosage: 60mg | |||
|---|---|---|---|
| Package (num) | Per pill | Price | Buy |
| 30 | $1.37 | $41.00 (0%) | 🛒 Add to cart |
| 60 | $1.10 | $82.00 $66.00 (20%) | 🛒 Add to cart |
| 90 | $1.01 | $123.00 $91.00 (26%) | 🛒 Add to cart |
| 120 | $0.97 | $164.00 $117.00 (29%) | 🛒 Add to cart |
| 180 | $0.93 | $246.00 $168.00 (32%) | 🛒 Add to cart |
| 270 | $0.90 | $369.00 $243.00 (34%) | 🛒 Add to cart |
| 360 | $0.88
Best per pill | $492.00 $317.00 (36%) | 🛒 Add to cart |
Synonyms | |||
Alli (orlistat 60 mg) is the only FDA-approved over-the-counter weight loss aid that works by blocking the absorption of about 25% of dietary fat. Designed for adults with a BMI of 25 or higher, it complements a reduced-calorie, low-fat diet and regular physical activity to support gradual, sustainable weight management. Backed by extensive clinical research, Alli offers a non-stimulant, non-systemic mechanism of action, making it a trusted option for individuals committed to a structured weight loss journey under appropriate guidance.
Features
- Contains 60 mg of orlistat per capsule, the only FDA-approved OTC weight loss medication
- Non-systemic mode of action: works locally in the digestive tract
- Blocks approximately 25% of dietary fat from being absorbed
- Gluten-free formulation, suitable for individuals with gluten sensitivity
- Packaged with accessible resources including a weight loss support plan and dietary guidance
Benefits
- Supports clinically meaningful weight loss when combined with diet and exercise
- Encourages adherence to healthier eating habits by providing tangible feedback on high-fat meals
- Reduces caloric intake efficiently without affecting central nervous system function
- Helps users develop long-term, sustainable weight management strategies
- Provides a non-stimulant alternative to appetite suppressants, minimizing jitteriness or sleep disruption
- Empowers users with educational tools to make informed nutritional choices
Common use
Alli is commonly used by adults aged 18 and older with an initial body mass index (BMI) of 25 or greater as part of a comprehensive weight management plan. It is intended for individuals seeking to lose weight gradually and sustainably, particularly those who have had difficulty achieving results through diet and exercise alone. Typical users include people with obesity-related health concerns or those aiming to reduce the risk of weight-related comorbidities. Alli is not intended for cosmetic weight loss or use in individuals with normal body weight.
Dosage and direction
Take one 60 mg capsule with water immediately before, during, or up to one hour after each main meal that contains fat. Do not exceed three capsules per day. If a meal is missed or contains no fat, omit the dose. It is recommended to distribute daily fat intake evenly across meals and keep fat consumption to approximately 15 grams per meal. Supplementation with a multivitamin containing fat-soluble vitamins (A, D, E, K) is advised—take at least 2 hours before or after Alli to ensure proper absorption.
Precautions
- Not for use by individuals under 18 years of age.
- Should not be used during pregnancy or breastfeeding.
- Use with caution in patients with a history of hyperoxaluria or calcium oxalate nephrolithiasis.
- Monitor for signs of liver injury (e.g., jaundice, dark urine); discontinue use if symptoms occur.
- May reduce absorption of fat-soluble vitamins and some medications; take multivitamins separately.
- Not recommended for use beyond two years without medical supervision.
Contraindications
- Chronic malabsorption syndrome
- Cholestasis
- Hypersensitivity to orlistat or any component of the formulation
- Organ transplant recipients on cyclosporine therapy
- Patients with anorexia nervosa or bulimia
Possible side effects
Common side effects are largely gastrointestinal and related to fat excretion. These may include:
- Oily spotting
- Gas with discharge
- Urgent bowel movements
- Fatty or oily stools
- Increased defecation
- Abdominal discomfort or pain
These effects are generally mild to moderate, decrease over time, and can be minimized by adhering to a low-fat diet. Rare but serious side effects may include severe liver injury, kidney stones, or pancreatitis. Discontinue use and seek medical attention if unusual symptoms occur.
Drug interaction
Orlistat may interact with:
- Cyclosporine: reduced absorption; administer at least 2 hours apart.
- Warfarin: monitor INR closely due to possible changes in vitamin K absorption.
- Levothyroxine: may reduce efficacy; administer at least 4 hours apart.
- Antiepileptic drugs (e.g., valproate, lamotrigine): potential reduced absorption.
- Amiodarone: monitor levels and efficacy.
- Antiretroviral drugs: use with caution and under medical supervision.
Always inform your healthcare provider of all medications and supplements you are taking.
Missed dose
If you miss a dose, take it as soon as you remember with your meal or within an hour after eating. However, if it is almost time for your next meal, skip the missed dose and resume your regular schedule. Do not double the dose to make up for a missed one.
Overdose
There have been no reports of serious adverse events from orlistat overdose. Single doses up to 800 mg have been studied without severe effects. In case of suspected overdose, symptomatic and supportive care is recommended. High doses may exacerbate gastrointestinal side effects. Contact a poison control center or healthcare provider for guidance.
Storage
Store at room temperature (20–25°C or 68–77°F). Keep the bottle tightly closed in a dry place, away from direct light and moisture. Do not freeze. Keep out of reach of children and pets.
Disclaimer
This information is intended for educational purposes and does not replace professional medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider before starting any new medication or weight management program, especially if you have underlying health conditions or are taking other medications. Individual results may vary.
Reviews
Clinical studies and user testimonials consistently highlight Alli’s effectiveness when used as directed. In a 6-month trial, participants using orlistat 60 mg lost significantly more weight than those on placebo alongside a reduced-calorie diet. Users frequently report improved dietary awareness and sustained motivation, though many emphasize the necessity of strict adherence to a low-fat diet to minimize gastrointestinal effects. Overall, Alli is regarded as a useful tool for individuals committed to a structured, long-term weight management strategy.