Antivert: Effective Relief from Vertigo and Motion Sickness
Antivert
| Product dosage: 25mg | |||
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Synonyms | |||
Antivert (meclizine hydrochloride) is a trusted prescription medication specifically formulated to prevent and treat symptoms associated with vertigo, dizziness, and motion sickness. As an antihistamine with central nervous system effects, it works by inhibiting signals in the brain responsible for nausea and balance disturbances. Clinically proven and widely recommended by healthcare professionals, Antivert offers rapid and sustained relief, allowing patients to regain control over daily activities and improve overall quality of life. Its well-established safety profile and efficacy make it a first-line choice for managing vestibular disorders.
Features
- Active ingredient: Meclizine hydrochloride 12.5 mg or 25 mg per tablet
- Pharmacological class: Antihistamine (H1 receptor antagonist) with antiemetic and antivertigo properties
- Administration: Oral tablet formulation
- Onset of action: Typically within 1 hour
- Duration of effect: Up to 24 hours
- Available by prescription only
Benefits
- Provides rapid relief from vertigo, dizziness, and associated nausea
- Prevents motion sickness during travel by air, sea, or land
- Reduces the frequency and severity of vestibular disorder episodes
- Enables participation in daily activities with improved balance and comfort
- Minimizes the impact of inner ear disturbances on quality of life
- Offers predictable, long-lasting symptom control with convenient once-daily dosing
Common use
Antivert is primarily indicated for the management of vertigo associated with diseases affecting the vestibular system, such as Ménière’s disease, labyrinthitis, and vestibular neuronitis. It is also widely prescribed for the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness. Healthcare providers may recommend Antivert for off-label uses in certain cases of postoperative nausea or radiation-induced dizziness, though such applications require careful medical supervision.
Dosage and direction
For vertigo: The recommended adult dosage is 25–100 mg daily, divided into doses as directed by a physician. Typically, 25 mg taken three times daily or 50 mg twice daily is prescribed, with adjustments based on symptom severity and patient response.
For motion sickness: The usual prophylactic dose is 25–50 mg taken one hour before travel, with repeat doses every 24 hours for the duration of the journey if necessary.
Tablets should be swallowed whole with water, with or without food. Dosage for pediatric patients (under age 12) must be determined by a healthcare provider based on weight and clinical indication. Geriatric patients or those with hepatic impairment may require dosage adjustments.
Precautions
Patients should avoid alcohol and CNS depressants while taking Antivert due to additive sedative effects. Use with caution in individuals with:
- Glaucoma (particularly angle-closure)
- Prostatic hypertrophy or urinary retention
- Respiratory conditions such as asthma or COPD
- Cardiovascular disorders
- Hepatic impairment
Antivert may cause drowsiness; patients should not operate machinery or drive until they know how the medication affects them. Elderly patients are more susceptible to anticholinergic effects, including confusion and dizziness. Pregnancy Category B: Use only if clearly needed after consulting a physician. Not recommended during breastfeeding.
Contraindications
Antivert is contraindicated in patients with:
- Known hypersensitivity to meclizine or any component of the formulation
- Concurrent use of monoamine oxidase inhibitors (MAOIs)
- Severe liver impairment
- Neonates and infants under 2 years of age
Possible side effects
Common side effects (≥1%):
- Drowsiness
- Dry mouth
- Headache
- Fatigue
Less common side effects:
- Blurred vision
- Constipation
- Nervousness or excitation (paradoxical reaction in children)
- Palpitations
- Urinary retention
Rare but serious side effects requiring immediate medical attention:
- Severe hypotension
- Allergic reactions (rash, itching, swelling, difficulty breathing)
- Tachycardia or arrhythmias
- Significant CNS depression
Drug interaction
Antivert may interact with:
- CNS depressants (alcohol, benzodiazepines, opioids, barbiturates): Enhanced sedation
- Anticholinergic agents (atropine, tricyclic antidepressants): Additive anticholinergic effects
- MAOIs: Risk of hypertensive crisis (contraindicated)
- Other antihistamines: Increased risk of side effects
- Drugs metabolized by CYP2D6: Potential altered efficacy
Missed dose
If a dose is missed, take it as soon as remembered unless it is nearly time for the next dose. Do not double the dose to catch up. Resume the regular dosing schedule. For motion sickness prophylaxis, take the missed dose as soon as possible if still during the travel period.
Overdose
Symptoms of overdose may include severe drowsiness, confusion, hallucinations, seizures, tachycardia, dry mouth, flushed skin, and respiratory depression. In case of suspected overdose, seek immediate medical attention or contact a poison control center. Treatment is supportive and may include gastric lavage, activated charcoal, and management of symptoms. There is no specific antidote.
Storage
Store at room temperature (15–30°C or 59–86°F) in a tightly closed container. Protect from light and moisture. Keep out of reach of children and pets. Do not use after the expiration date printed on the packaging. Dispose of unused medication properly according to local guidelines or through a drug take-back program.
Disclaimer
This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before starting, changing, or discontinuing any medication. The prescribing physician should be informed of all medical conditions and concurrent medications. Individual responses to Antivert may vary.
Reviews
Clinical studies and patient reports consistently demonstrate Antivert’s efficacy in managing vertigo and motion sickness. In controlled trials, over 80% of patients experienced significant improvement in vertigo symptoms within one week of treatment. Motion sickness prevention efficacy exceeds 90% when taken prophylactically. Patients frequently report restored ability to perform daily activities and travel comfortably. Most adverse effects are mild and transient, with drowsiness being the most commonly reported issue that often diminishes with continued use.