Dutas: Advanced Treatment for Benign Prostatic Hyperplasia Relief
Dutas
| Product dosage: 0.5mg | |||
|---|---|---|---|
| Package (num) | Per pill | Price | Buy |
| 30 | $1.90 | $57.00 (0%) | 🛒 Add to cart |
| 60 | $1.80 | $114.00 $108.00 (5%) | 🛒 Add to cart |
| 90 | $1.77 | $171.00 $159.00 (7%) | 🛒 Add to cart |
| 120 | $1.75 | $228.00 $210.00 (8%) | 🛒 Add to cart |
| 180 | $1.73 | $342.00 $312.00 (9%) | 🛒 Add to cart |
| 270 | $1.72
Best per pill | $513.00 $464.00 (10%) | 🛒 Add to cart |
Dutas is a prescription medication specifically formulated for the management of symptomatic benign prostatic hyperplasia (BPH). It combines two active ingredients, dutasteride and tamsulosin, to provide a dual mechanism of action that addresses both the static and dynamic components of urinary obstruction. This comprehensive approach helps improve urinary flow, reduce symptoms of BPH, and prevent disease progression. Clinical studies support its efficacy in enhancing quality of life for men affected by this condition.
Features
- Contains 0.5 mg dutasteride and 0.4 mg tamsulosin hydrochloride per capsule
- Dual 5-alpha-reductase inhibitor and alpha-1 adrenergic blocker
- Gelatin-based, opaque capsules for oral administration
- Available in blister packs of 10 or 30 capsules
- Requires prescription and medical supervision
- Manufactured under strict pharmaceutical quality standards
Benefits
- Significantly improves urinary flow rate and reduces symptoms like hesitancy, weak stream, and nocturia
- Reduces the risk of acute urinary retention and the need for BPH-related surgery
- Addresses both hormonal and muscular components of prostate enlargement
- Provides convenient once-daily dosing for consistent therapeutic effect
- Helps prevent further prostate growth with long-term use
- May improve overall quality of life by relieving bothersome urinary symptoms
Common use
Dutas is primarily indicated for the treatment of symptomatic benign prostatic hyperplasia in men with an enlarged prostate. It is prescribed for patients who require combination therapy to address both the size-related obstruction and the smooth muscle tension in the prostate and bladder neck. The medication is typically used in patients with moderate to severe symptoms who have not responded adequately to monotherapy with either alpha-blockers or 5-alpha-reductase inhibitors alone.
Dosage and direction
The recommended dosage is one capsule (0.5 mg dutasteride/0.4 mg tamsulosin) taken orally once daily, approximately 30 minutes after the same meal each day. The capsule should be swallowed whole with a glass of water and should not be crushed or chewed. Patients should maintain a consistent dosing schedule and not discontinue treatment without consulting their physician. Clinical improvement may be observed within 1-2 weeks for urinary flow symptoms, though maximum benefit for prostate size reduction may take up to 6 months of continuous therapy.
Precautions
Patients should be informed that dutasteride, a component of Dutas, may affect PSA values and prostate cancer detection. A new baseline PSA should be established after 6 months of treatment, and any confirmed increase in PSA while on Dutas should be carefully evaluated. Orthostatic hypotension may occur, particularly at the initiation of therapy. Patients should be cautious when rising from sitting or lying positions. Dutas should not be handled by women who are pregnant or may become pregnant due to the risk of absorption through the skin and potential fetal harm.
Contraindications
Dutas is contraindicated in patients with known hypersensitivity to dutasteride, tamsulosin, other 5-alpha-reductase inhibitors, or any component of the formulation. It should not be used in women or children. Concomitant use with other alpha-adrenergic blocking agents is contraindicated. Patients with severe hepatic impairment should not use this medication. Additionally, it is contraindicated in patients with a history of orthostatic hypotension or who are taking strong CYP3A4 inhibitors.
Possible side effects
Common side effects may include ejaculation disorders (including decreased ejaculate volume), erectile dysfunction, decreased libido, dizziness, and orthostatic hypotension. Less frequently reported effects include breast tenderness and enlargement, rhinitis, and intraoperative floppy iris syndrome during cataract surgery. Rare but serious side effects may include severe allergic reactions, angioedema, and priapism. Patients should report any persistent or bothersome side effects to their healthcare provider.
Drug interaction
Dutas may interact with other alpha-adrenergic blockers, potentially increasing the risk of hypotension. Concomitant use with strong CYP3A4 inhibitors (such as ketoconazole) may increase tamsulosin exposure. PDE5 inhibitors may potentiate the blood pressure-lowering effects. Warfarin may require monitoring as dutasteride may affect its metabolism. Other 5-alpha-reductase inhibitors should not be used concurrently. Physicians should review all medications, including over-the-counter drugs and supplements, before prescribing Dutas.
Missed dose
If a dose is missed, it should be taken as soon as remembered unless it is almost time for the next scheduled dose. In that case, the missed dose should be skipped and the regular dosing schedule resumed. Patients should not take a double dose to make up for a missed one. Consistent daily dosing is important for maintaining therapeutic effect, so patients should establish a routine to minimize missed doses.
Overdose
In case of overdose, supportive measures should be implemented. Symptoms may include severe dizziness, fainting, and pronounced orthostatic hypotension. Cardiovascular monitoring may be necessary. Since tamsulosin is highly protein-bound, dialysis is not likely to be effective. There is no specific antidote for Dutas overdose. Patients experiencing suspected overdose should seek immediate medical attention or contact a poison control center.
Storage
Store at room temperature (15-30°C or 59-86°F) in the original container, protected from light and moisture. Keep out of reach of children and pets. Do not use after the expiration date printed on the packaging. Unused medication should be disposed of properly according to local regulations, preferably through medication take-back programs.
Disclaimer
This information is provided for educational purposes only and does not constitute medical advice. Dutas is a prescription medication that should only be used under the supervision of a qualified healthcare professional. Patients should not initiate or discontinue treatment without consulting their physician. Individual results may vary, and not all patients will experience the same benefits or side effects.
Reviews
Clinical studies have demonstrated that Dutas provides significant improvement in both symptoms and objective measures of BPH compared to monotherapy. In randomized controlled trials, combination therapy showed superior improvement in IPSS scores and maximum urinary flow rates versus either component alone. Long-term studies indicate sustained efficacy and good tolerability profile. Many patients report improved quality of life and satisfaction with treatment outcomes, though individual experiences with side effects vary.