Unisom SleepTabs: Clinically Proven Sleep Aid for Restful Nights
Unisom
| Product dosage: 25mg | |||
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Synonyms | |||
Unisom SleepTabs, containing the active ingredient doxylamine succinate, is an over-the-counter sleep aid specifically formulated to address occasional sleeplessness. As a first-generation antihistamine with sedative properties, it works by blocking histamine receptors in the brain, promoting drowsiness and facilitating sleep onset. Trusted by healthcare professionals and consumers for decades, Unisom provides non-habit forming sleep support when used as directed for short-term management of insomnia symptoms.
Features
- Contains 25 mg doxylamine succinate per tablet
- Non-habit forming formula when used as directed
- No analgesic components (pain reliever-free)
- Rapid-dissolve tablet formulation
- Suitable for adults and children 12 years and older
- Available without prescription
Benefits
- Reduces time to sleep onset by promoting drowsiness
- Helps maintain sleep throughout the night
- Provides next-day alertness without grogginess when dosed properly
- Non-narcotic alternative to prescription sleep aids
- Cost-effective OTC solution for occasional sleeplessness
- Established safety profile with decades of clinical use
Common use
Unisom SleepTabs are indicated for the relief of occasional sleeplessness and difficulty falling asleep. The medication is appropriate for short-term use, typically not exceeding two weeks unless directed by a healthcare provider. Patients experiencing transient insomnia due to stress, travel, or schedule disruptions may benefit from this sleep aid. It is particularly useful for those who have difficulty initiating sleep rather than maintaining sleep throughout the night.
Dosage and direction
The recommended dosage for adults and children 12 years of age and older is one tablet (25 mg doxylamine succinate) taken 30 minutes before bedtime. The tablet should be swallowed whole with water. Do not crush or chew. This medication should be taken only when you can devote 7-8 hours to sleep. Do not take more than one tablet in 24 hours. Use for more than two weeks should be supervised by a healthcare professional. For older adults (65+), consider starting with a half tablet due to potential increased sensitivity.
Precautions
Avoid alcohol consumption while taking Unisom, as it may increase drowsiness and impairment. Exercise caution when driving, operating machinery, or performing activities requiring alertness the following day. This medication may cause drowsiness that persists into the next day, particularly in elderly patients. Not recommended for use during pregnancy without medical supervision. Those with breathing problems, glaucoma, urinary retention, or prostate enlargement should consult a healthcare provider before use. Do not use with other sedating medications without medical advice.
Contraindications
Unisom SleepTabs are contraindicated in patients with known hypersensitivity to doxylamine succinate or any component of the formulation. Should not be used by children under 12 years of age. Contraindicated in patients with narrow-angle glaucoma, severe hypertension, bronchial asthma, peptic ulcer, or bladder neck obstruction. Not recommended for patients taking monoamine oxidase inhibitors (MAOIs) or within 14 days of discontinuing MAOI therapy.
Possible side effects
Common side effects may include drowsiness, dizziness, dry mouth, nose and throat, blurred vision, upset stomach, constipation, or headache. These effects are generally mild and tend to diminish with continued use. Less frequently, users may experience excitation (especially in children), nervousness, restlessness, or palpitations. Serious side effects requiring medical attention include difficulty urinating, irregular heartbeat, severe dizziness, or confusion. Allergic reactions, though rare, may present as rash, itching, swelling, severe dizziness, or trouble breathing.
Drug interaction
Doxylamine succinate may interact with other central nervous system depressants including alcohol, sedatives, tranquilizers, barbiturates, and opioid pain medications, potentially enhancing sedative effects. Anticholinergic drugs (such as atropine, scopolamine) may compound anticholinergic side effects. MAO inhibitors may prolong and intensify anticholinergic effects. Concurrent use with other antihistamines should be avoided. Consult a healthcare provider before combining with antidepressants, antipsychotics, or Parkinson’s disease medications.
Missed dose
If you forget to take Unisom at your scheduled time, take it only if you can still get a full 7-8 hours of sleep. Do not double the dose to make up for a missed tablet. Taking the medication too late may result in next-day drowsiness and impairment. If you miss a dose entirely, simply resume your regular dosing schedule the following night. Do not take more than one tablet in a 24-hour period.
Overdose
In case of overdose, seek immediate medical attention or contact a Poison Control Center. Symptoms of overdose may include extreme drowsiness, confusion, agitation, nervousness, dry mouth, large pupils, flushing, fever, shaking, insomnia, hallucinations, seizures, or unconsciousness. In severe cases, overdose may lead to respiratory depression, cardiovascular collapse, or death. Treatment is supportive and may include gastric lavage, activated charcoal, and monitoring of vital signs.
Storage
Store at room temperature (68-77°F/20-25°C) in a dry place protected from light and moisture. Keep the bottle tightly closed and store in the original container. Keep out of reach of children and pets. Do not use if the blister pack is broken or tablets show signs of deterioration. Properly discard any unused medication after the expiration date printed on the packaging.
Disclaimer
This information is for educational purposes only and does not constitute medical advice. Always consult with a healthcare professional before starting any new medication, especially if you have pre-existing medical conditions or are taking other medications. Individual responses to medication may vary. Use only as directed on the product labeling or as prescribed by your healthcare provider.
Reviews
Clinical studies demonstrate that doxylamine succinate significantly reduces sleep onset latency and improves sleep quality compared to placebo. Patient reviews consistently report effective sleep initiation with proper dosing, though some users note next-day drowsiness if taken without adequate sleep time. Healthcare professionals appreciate its non-habit forming profile when used appropriately for short-term sleep management. The American Academy of Sleep Medicine recognizes antihistamines like doxylamine as an option for transient insomnia treatment.