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Diphenhydramine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include runny nose, sneezing, watery eyes, and itching of the nose and throat. Diphenhydramine is also used to suppress coughs, to relieve the symptoms of motion sickness, and to treat mild forms of Parkinson's disease. Diphenhydramine can be taken orally or injected intravenously. It is also available in a topical cream, which is applied to the skin. The oral and intravenous forms of diphenhydramine are used to treat severe allergic reactions (anaphylaxis) and to treat or prevent symptoms of poisoning. The topical cream is used to relieve itching and pain from insect bites, sunburn, and other skin conditions. Diphenhydramine is also used in combination with other drugs to treat night-time cold symptoms and to relieve the symptoms of Parkinson's disease. Diphenhydramine is in a class of drugs called antihistamines. Antihistamines work by blocking the action of histamine, a substance in the body that is responsible for many of the symptoms of an allergic reaction.

Uses

Diphenhydramine is used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include runny nose, sneezing, watery eyes, and itching of the nose and throat. Diphenhydramine is also used to suppress coughs, to relieve the symptoms of motion sickness, and to treat mild forms of Parkinson's disease. Diphenhydramine can be taken orally or injected intravenously. It is also available in a topical cream, which is applied to the skin.

Side Effects

Diphenhydramine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • drowsiness
  • dizziness
  • loss of coordination
  • dry mouth
  • blurred vision
  • constipation
  • urinating more or less than usual
  • nausea
  • vomiting
  • stomach pain
  • weight gain
  • trouble sleeping

If you experience any of the following symptoms, call your doctor immediately:

  • skin rash
  • hives
  • wheezing or difficulty breathing
  • swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
  • hoarseness
  • chest pain
  • fast, irregular, or pounding heartbeat
  • nervousness
  • agitation
  • hallucinations
  • seizures

Interactions

Certain drugs should not be used together. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Other Names

Benadryl, Allerdryl, Banophen, Bedtime, Belix, Benadryl Allergy, Benadryl D, Benaject-50, Benalyte, Ben-tann, Butix, Caladryl, Caladryl Allergy, Caladryl Clear, Calmine, Calmine Forte, Calm-X, Children's Allergy, Children's Benadryl Allergy, Children's Diphenhydramine, Children's Zyrtec Allergy, Cosy, D-Hist, Dermamycin, Diphamine, Diphen, Diphen Cough, Diphenhist, Diphenhydramin, Diphenhydramine, Diphenhydramine HCl, Diphenhydramine Hydrochloride, Diphenhydramine Salicylate, Dytan, Genahist, Histaxin, Hydroxyzine, Kwellada-P, Nytol QuickCaps, PediaCare Children's Allergy, Q-Pap, Q-Pap Children's, Siladryl, Silphen Cough, Simply Sleep, Sleep-Eze D, Sleep-Eze D-60, Snore Relief, Sominex, Sominex Maximum Strength Caplets, Sudafed, Sudafed Sinus, Triaminic Thin Strips Allergy, Unisom SleepGels, Valu-Dryl, Vanamine PD, Z-Sleep, ZzzQuil

This product is available in the following dosage forms: Tablet Capsule Liquid Suspension Suppository Injection Cream Solution Concentrate Packet Benadryl online is available in the following strengths: 25 mg 50 mg 75 mg 100 mg 150 mg 200 mg 300 mg The following dosage forms are available for Benadryl online: Tablets: 25 mg, 50 mg, 75 mg, 100 mg, 150 mg, 200 mg, 300 mg Capsules: 25 mg, 50 mg, 75 mg, 100 mg, 150 mg, 200 mg, 300 mg Liquid: 5 mL, 15 mL, 30 mL Suspension: 5 mL, 15 mL, 30 mL Suppository: 12.5 mg, 25 mg, 50 mg, 75 mg, 100 mg Injection: 25 mg/mL, 50 mg/mL Cream: 1%, 2% Solution: 1%, 2% Concentrate: 2.5 mg/mL Packet: 25 mg, 50 mg, 75 mg, 100 mg, 150 mg, 200 mg, 300 mg

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