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Minomycin (minocycline) is a tetracycline antibiotic that fights bacteria in the body. Minomycin is used to treat many different bacterial infections, such as urinary tract infections, acne, gonorrhea, and chlamydia, periodontitis (gum disease), and others. Minomycin is also used to treat blemishes, bumps, and acne-like lesions caused by rosacea.

Do not use this medication if you are allergic to minocycline or to other tetracycline antibiotics such as demeclocycline (Declomycin), doxycycline (Adoxa, Doryx, Oracea, Vibramycin), or tetracycline (Brodspec, Panmycin, Sumycin, Tetracap).

To make sure you can safely take minocycline, tell your doctor if you have any of these other conditions:

  • kidney disease (or if you are on dialysis);
  • liver disease;
  • asthma or sulfite allergy;
  • history of diarrhoea caused by taking antibiotics;
  • stomach or intestinal problems (especially colitis);
  • pancreatitis;
  • seizures;
  • an unusual or allergic reaction to minocycline, other antibiotics or medicines, foods, dyes, or preservatives;
  • pregnant or trying to get pregnant;
  • breast-feeding.

Some medicines may interact with Minomycin. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • barbiturates (eg, phenobarbital), carbamazepine, or hydantoins (eg, phenytoin) because they may decrease Minomycin 's effectiveness;
  • digoxin or live vaccines because the risk of their side effects may be increased by Minomycin;
  • methoxyflurane or oral contraceptives (birth control pills) because their effectiveness may be decreased by Minomycin.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Minomycin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

  • Minomycin may cause live bacterial vaccines (eg, typhoid vaccine) to not work as well. Do not have any immunizations / vaccinations while using Minomycin unless your doctor tells you to.
  • Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Minomycin can make your skin more sensitive to sunlight and sunburn may result. Use a sunscreen (minimum SPF 15) and wear protective clothing if you must be out in the sun.
  • Diarrhea is a common problem caused by antibiotics which usually ends when the antibiotic is discontinued. Sometimes after starting treatment with antibiotics, patients can develop watery and bloody stools (with or without stomach cramps and fever) even as late as two or more months after having taken the last dose of the antibiotic. If this occurs, patients should contact their physician as soon as possible.
  • Minomycin should not be used in CHILDREN younger than 8 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: Minomycin has been shown to cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Minomycin while you are pregnant. Minomycin is found in breast milk. If you are or will be breast-feeding while you use Minomycin, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Minomycin:

  • All medicines may cause side effects, but many people have no, or minor, side effects.
  • Check with your doctor if any of these most COMMON side effects persist or become bothersome:
    • diarrhoea;
    • dizziness;
    • headache;
    • loss of appetite;
    • mild stomach pain;
    • nausea;
    • skin rash or itching;
    • tiredness.
  • Seek medical attention right away if any of these SEVERE side effects occur:
    • severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue);
    • bloody stools;
    • changes in skin colour;
    • dark urine;
    • fever, chills, or sore throat;
    • joint pain;
    • mood or mental changes (eg, depression);
    • muscle pain or weakness;
    • new or worsening irritation or swelling of a wound;
    • red, swollen, blistered, or peeling skin;
    • seizures;
    • severe or persistent diarrhoea;
    • severe or persistent dizziness or headache;
    • stomach pain or cramps;
    • unusual bruising or bleeding;
    • unusual tiredness or weakness;
    • vaginal irritation or discharge;
    • vision changes;
    • yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-F

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